Association Between Resuscitation Orders and Mortality in ICU Patients

Karolinska Institute

Status: Active, not recruiting

Conditions: Critical Illness

Treatments: Other: Resuscitation orders

Study type: Observational

Funder types: Other

Identifiers

NCT06373068

Resuscitation Orders ICU

Details and patient eligibility

About

The hypothesis of the study is that a resuscitation order other than full code is associated with increased mortality among critically ill patients. By incorporating conventional variables associated with death such as age, sex, and Simplified Acute Physiological Score, as well as including the new Clinical Frailty Scale in a statistical model, the aim is to investigate whether there is still an increased risk of death that remains unexplained.

Enrollment: 1,500 estimated patients

Sex: All

Ages: 16+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Admitted to ICU

Exclusion criteria

• Second or subsequent admission to ICU during the study period.

Trial design

1,500 participants in 3 patient groups

Full code

Description:

Patients without any restrictions on the types of treatments available, such as cardiopulmonary resuscitation, intubation, various life support measures, surgery, etc., if indicated.

Treatment:

Other: Resuscitation orders

Simple Do-Not-Attempt-Resuscitation

Description:

The only treatment limitation in patient care is cardiopulmonary resuscitation in case of a cardiac arrest. All other indicated devices or treatments may still be utilized.

Treatment:

Other: Resuscitation orders

Do not attempt resuscitation with limited scope

Description:

The treatment limitation in patient care includes not performing cardiopulmonary resuscitation and also involve additional limitations, typically including various life support measures.

Treatment:

Other: Resuscitation orders