Association Between Testosterone Levels and COPD Severity (COPDTESTO)

Hospital Italiano de Buenos Aires

Status: Unknown

Conditions: Chronic Obstructive Pulmonary Disease; Hypogonadism

Study type: Observational

Funder types: Other

Identifiers

NCT02824809

2413

Details and patient eligibility

About

The Aims of the study are estimate the association between the severity of COPD and free testosterone level and the prevalence of hypogonadism in adult men with stable COPD

Enrollment: 150 estimated patients

Sex: Male

Ages: 45+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Adults Men ≥ 45 years
• COPD defined according to clinical diagnosis and spirometry American thoracic society ( ATS) criteria
• Stable COPD without recent acute exacerbation (less than 2 weeks)

Exclusion criteria

• Refusal to participate or informed consent process
• Those who are under treatment with testosterone replacement or anti-androgens
• Comorbidities: Cirrhosis, Alcoholism, cryptorchidism, panhypopituitarism, Pituitary adenoma.
• Orchiectomy
• Systemic glucocorticoids (equivalent dose ≥ 4 mg of prednisone in the last 3 weeks).
• Relative and absolute contraindications for spirometry.