Association of Genetic Polymorphism and Acute Kidney Injury After Liver Transplantation

Yonsei University

Status: Completed

Conditions: Liver Transplantation

Study type: Observational

Funder types: Other

Identifiers

NCT02489474

4-2015-0411

Details and patient eligibility

About

Some of the liver transplantation recipients experience postoperative acute kidney injury due to various causes including genetic factors. Prevention of postoperative acute kidney injury is essential for postoperative care in liver transplantation recipients. The aim of this study is to investigate the relationship between gene polymorphisms which have been known to be associated with postoperative acute kidney injury, and the occurrence of acute kidney injury after liver transplantation.

Enrollment: 124 patients

Sex: All

Ages: 19 to 80 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

1. adult patients scheduled for liver transplantation

Exclusion criteria

1. Patients on dialysis
2. patients not able to read, or understand the consent form
3. ethnicity, other than asian
4. patients refusal

Trial design

124 participants in 1 patient group

Recipients undergoing liver transplantation

Description:

Patients undergoing liver transplantation will be included and followed up during the first 72 hours post-liver transplantation in order to confirm the development of acute kidney injury. The patients will be divided into two groups (AKI group vs. non-AKI group) according to the development of acute kidney injury.