Association of Hb F Level With Clinical Severity of Beta Thalassemia

Nanfang Hospital, Southern Medical University

Status: Enrolling

Conditions: Beta Thalassemia

Treatments: Diagnostic Test: Hematological Phenotype Analysis

Study type: Observational

Funder types: Other

Identifiers

NCT04917978

HbF-Beta thalassemia

Details and patient eligibility

About

The production of Hb F after birth is an important factor in modifying the clinical severity of beta thalassemia because an increased gamma-globin level will bind the additional a-globin and form Hb F. The objective of this project is to evaluate the association of Hb F level with phenotypic diversity of patients with beta thalassemia.

Enrollment: 1,200 estimated patients

Sex: All

Volunteers: No Healthy Volunteers

Inclusion criteria

• Diagnosed with beta-thalassemia

Exclusion criteria

• Iron Deficiency Anemia

Trial design

1,200 participants in 1 patient group

beta thalassemia patients

Treatment:

Diagnostic Test: Hematological Phenotype Analysis