Association of Non-alcoholic Fatty Liver Disease and Coronary Artery Disease

Johann Wolfgang Goethe University Hospital

Status: Unknown

Conditions: Nonalcoholic Steatohepatitis (NASH)

Treatments: Device: Controlled Attenuation Parameter (CAP), Echosens, Paris, France; Device: Transient Elastography (FibroScan), Echosens, Paris, France

Study type: Interventional

Funder types: Other

Identifiers

NCT01638832

JWGUHMED1-005

Details and patient eligibility

About

This study will evaluate the association of non-alcoholic fatty liver disease and coronary artery disease. All patients presenting for coronary angiogram will receive the following examination:

• Transient Elastography and Controlled Attenuation Parameter using the FibroScan
• blood examination including biochemical markers The results of non-invasive liver steatosis and fibrosis measurement are compared with the results of coronary angiogram concerning the presence or absence of coronary artery disease.

Enrollment: 572 estimated patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Male or female, 18 years and older
• Written consent
• Coronary angiogram planned

Exclusion criteria

• Patients with mental diseases
• Pregnancy or lactation
• Ascites

Trial design

Primary purpose: Diagnostic

Allocation: N/A

Interventional model: Single Group Assignment

Masking: None (Open label)