Association of Periostin Levels and Chronic Sinusitis

University of Virginia

Status: Withdrawn

Conditions: Nasal Polyps; Sinusitis

Treatments: Other: Blood draw

Study type: Observational

Funder types: Other

Identifiers

NCT02071667

17123

Details and patient eligibility

About

The purpose of this study is to see if a protein in blood, called periostin, can determine if patients have chronic sinusitis. This protein is in everyone's body, but the level of the protein may indicate certain conditions such as chronic sinusitis. The investigators are interested in testing levels of periostin to see if they are higher or lower than patients without chronic sinusitis, just as periostin is higher in patients with asthma. All patients enrolled in this study will have chronic sinusitis without asthma.

Sex: All

Ages: 18 to 65 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Patients with sinus disease which requires surgical intervention
• Ability to understand and give informed consent

Exclusion criteria

• Previous diagnosis of asthma
• Positive methacholine challenge at screening
• Diagnosis of cystic fibrosis
• Concomitant use of systemic corticosteroids (except for those prescribed as part of standard pre-surgical treatment)

Trial design

0 participants in 1 patient group

Subjects who require sinus surgery

Treatment:

Other: Blood draw