Association of Plasma PTX3 Concentration and Outcomes of STEMI

Indonesian Cardiovascular Research Center

Status: Completed

Conditions: Coronary; Ischemic; STEMI

Treatments: Other: Plasma PTX3 concentration

Study type: Observational

Funder types: Other

Identifiers

NCT03894176

IndonesianCRC

Details and patient eligibility

About

335 of patients with STEMI treated by primary PCI were assayed for PTX3 measurement by ELISA method. The angiographic and clinical outcomes were evaluated according to the PTX3 concentration.

Full description

335 of patients with STEMI treated by primary PCI were assayed for PTX3 measurement by ELISA method using human PTX3 kit. Blood was drawn at the emergency department before primary PCI. The angiographic and clinical outcomes were evaluated and analyzed according to the PTX3 concentration. The angiographic outcome were thrombus grade on initial angiogram and final TIMI flow. The clinical outcome were ECG resolution after primary PCI and all-cause death at 30 days. The plasma PTX3 concentration was then compared based on the outcomes.

Enrollment: 335 patients

Sex: All

Volunteers: No Healthy Volunteers

Inclusion criteria

• Patients with acute STEMI with symptom onset <12 h undergoing primary PCI

Exclusion criteria

• Acute STEMI patients who received fibrinolytic therapy

Trial design

335 participants in 1 patient group

PTX3 concentration

Description:

First quartile, second quartile, third quartile and fourth quartile of PTX3 in ng/mL

Treatment:

Other: Plasma PTX3 concentration