Association of Plasma Transfusions and Invasive Fungal Infection (PT)

Army Medical University of People's Liberation Army

Status: Enrolling

Conditions: Invasive Fungal Infection; Plasma Administration; Neonatal Infection

Treatments: Drug: non-plasma transfusions; Drug: plasma transfusions

Study type: Observational

Funder types: Other

Identifiers

NCT03149562

plasma transfusions

Details and patient eligibility

About

Although lacking strong evidences, plasma transfusions are commonly used in critically ill neonates. To date, the relationships between plasma transfusions and nosocomial infection remain controversial and no study has reported the relationships between plasma transfusion and invasive fungal infection (IFI)

Full description

Our aim is to explore the association between plasma transfusions and IFI in critically ill neonates

Enrollment: 500 estimated patients

Sex: All

Ages: Under 24 hours old

Volunteers: No Healthy Volunteers

Inclusion criteria

• all critically ill neonates admitted in hospital

Exclusion criteria

• severe congenital abnormality;
• died within 24 hours or left neonatal intensive care unit within 24 hours according to their parents' decisions;
• parents' decision not to participate.

Trial design

500 participants in 2 patient groups

plasma transfusions

Description:

The critical ill neonates with plasma transfusions

Treatment:

Drug: plasma transfusions

non-plasma transfusions

Description:

The critical ill neonates without plasma transfusions

Treatment:

Drug: non-plasma transfusions