Associative Memory in Adults With an Autism Spectrum Disorder (MEM-T2A)

Caen University Hospital

Status: Unknown

Conditions: Autistic Disorder

Treatments: Device: Electroencephalography; Behavioral: Neuropsychological assesments

Study type: Interventional

Funder types: Other

Identifiers

NCT02279680

2013-AO1800-45

Details and patient eligibility

About

The objective of this multidisciplinary project is to explore the deficit of associative memory in ASD (Autistic Spectrum Disorder) that could result from abnormal brain connectivity. The hypothesis of abnormal functioning of the fronto-hippocampal network has been evocated but has never been tested. Hence, the present project will include two complementary assessments conducted on a group of adults aged from 18 to 30 with ASD compared to a control group matched in chronological age and intellectual quotient. The first assessment is devoted to the study of associative memory and its EEG correlates and the second focused on the investigation of perceptual strategies related to associative memory using the technique of Eye-tracking. Both behavioral and imaging data would provide new insights on the relationship between perception and memory in ASD.

Enrollment: 40 estimated patients

Sex: All

Ages: 18 to 30 years old

Volunteers: Accepts Healthy Volunteers

Inclusion and exclusion criteria

Inclusion Criteria:

• Adult between 18 and 30 years old
• right handed
• affiliated to the french national health care system
• ASD only for the group of patients

Exclusion criteria :

• mental retardation
• schizophrenia
• ADHD
• brain injury with lost of consciousness
• neurological disease

Trial design

Primary purpose: Health Services Research

Allocation: Non-Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

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40 participants in 2 patient groups

Patients

Other group

Description:

Adults between 18 and 30 years old right handing Patients with ASD

Treatment:

Device: Electroencephalography

Behavioral: Neuropsychological assesments

Healthy volunteers

Other group

Description:

Adults between 18 and 30 years old Right handing Healthy

Treatment:

Device: Electroencephalography

Behavioral: Neuropsychological assesments