Asymptomatic Flu Project (AFP)

Civil Hospices of Lyon

Status: Completed

Conditions: Influenza

Treatments: Other: Nasal swab; Biological: Blood sampling

Study type: Interventional

Funder types: Other

Identifiers

NCT02868658

69HCL16_0095

Details and patient eligibility

About

Although clinical presentation of influenza is often symptomatic, asymptomatic cases also occur. The knowledge of the incidence of asymptomatic influenza among healthcare workers is very important because of the risk of cross-transmission to hospitalized patients. The principal objective of the study is to estimate the incidence of symptomatic and asymptomatic influenza among healthcare workers in short-stay wards. The results of this study will lead to a better understanding of the burden of asymptomatic influenza among healthcare workers and might be used as an argument to increase influenza vaccine coverage among healthcare workers.

Enrollment: 289 patients

Sex: All

Ages: 18+ years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Volunteer health-care workers
• Working in the following wards: short-stay, inpatient (including ICU) and emergency

Exclusion criteria

• Presence of influenza symptoms at enrolment
• Programmed absence (maternity leave, vacation, etc.)
• Administrative agents

Trial design

Primary purpose: Prevention

Allocation: N/A

Interventional model: Single Group Assignment

Masking: None (Open label)

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289 participants in 1 patient group

Health-care workers

Experimental group

Description:

Health-care workers recruited in the study will have blood sampling and naso-pharyngeal bottle-brush sampling

Treatment:

Biological: Blood sampling

Other: Nasal swab