At Home Brain Stimulation Studies of Memory and Memory Awareness (remTDCS)

Brooklyn College of the City University of New York

Status: Unknown

Conditions: Healthy

Treatments: Device: remotely supervised transcranial direct current stimulation

Study type: Interventional

Funder types: Other; NIH

Identifiers

NCT04749719

SC3GM121192 (U.S. NIH Grant/Contract)

42037

Details and patient eligibility

About

The main goal of this research is to determine the role of several brain regions in memory processes and cognitive functions. Participants will be remotely supervised via video chat while self-administering tDCS, a form of non-invasive brain stimulation. Before participating in the experiment, participants will be properly trained on use of the remote tDCS device and screened for eligibility. While using the tDCS device, participants will be engaging in tasks that assess different aspects of memory and executive functioning. By using remotely supervised tDCS while participants are completing these cognitive tasks, we will be able to make causal claims about the role of the targeted brain regions in different cognitive processes.

Enrollment: 36 estimated patients

Sex: All

Ages: 18 to 35 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• between the ages of 18-35
• normal or corrected to normal vision
• fluent in English and speaking English since age 5
• right handed

Exclusion criteria

• chronic skin disease or medical skin condition
• unhealed wound or open skin on the scalp, face, neck, or forehead
• metal or electrode implants (e.g., cochlear implants, pacemakers, metal plates, rods, or screws in their head; for complete detail, see the screening form)
• seizures or a family history of seizures, or are taking medications with a lowered seizure threshold
• pregnant or lactating
• any neurologic or psychiatric diseases
• certain hair styles (dreadlocks, cornrows, etc) or hair coverings (e.g., wigs, hajibs, etc that will not be removed; note that a request can be made for an experimenter of a specific gender)

Trial design

Primary purpose: Basic Science

Allocation: Randomized

Interventional model: Crossover Assignment

Masking: Double Blind

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36 participants in 2 patient groups

DLPFC stimulation

Experimental group

Description:

F3-SO montage or OLE optimized with 2 mA stimulation for up to 30 min during memory and metamemory task.

Treatment:

Device: remotely supervised transcranial direct current stimulation

Sham tDCS

Sham Comparator group

Description:

F3-SO montage or OLE optimized with sham stimulation for up to 30 min during memory and metamemory task.

Treatment:

Device: remotely supervised transcranial direct current stimulation