ATM Variants in Radiotherapy Patients

University of Wisconsin (UW)

Status: Completed

Conditions: Radiotherapy

Study type: Observational

Funder types: Other

Identifiers

NCT00214227

A533300 (Other Identifier)

RO05305

SMPH/HUMAN ONCOLOGY (Other Identifier)

2005-0122 (Other Identifier)

Details and patient eligibility

About

The purpose of this study is to compare the baseline incidence of variant alleles in the ATM and/or other DNA repair genes present in the Native American population versus the non-Native American population. It is thought that a higher baseline incidence of the variant alleles in the ATM gene may correlate to higher rates and higher grades of radiation toxicities noted in the Native American population.

Enrollment: 60 patients

Sex: Male

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion and exclusion criteria

Inclusion Criteria:

• Indication for radiotherapy.
• Ability or desire to donate a blood sample and be followed closely for radiation toxicities