Atopy Patch Test in Normal Population : Pilot Study

Mahidol University

Status and phase: Completed; Phase 1

Conditions: Normal

Treatments: Device: Atopy patch test with food allergen

Study type: Interventional

Funder types: Other

Identifiers

NCT01156038

599/2552(EC4)

Details and patient eligibility

About

Atopy patch test in normal population

Full description

The initial diagnostic work up of suspected food allergy includes patient's history, skin prick test (SPT), measurement of food specific immunoglobulin E (IgE) with serological assays, and more recently the atopy patch test. A positive SPT seems to reflect early reactions to food challenges, whereas the atopy patch test has a high diagnostic efficacy for late phase clinical reactions. The purpose of this study was to evaluate atopy patch test reaction in non-atopic population.

Enrollment: 15 patients

Sex: All

Ages: 18 to 40 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Healthy volunteer
• Age 18-40 yrs
• Volunteer sign for informed consent

Exclusion criteria

• who have dermographism
• who have chronic disease eg.autoimmune disease, immune deficiency, cancer or allergic disease
• pregnant women
• who have severe eczema
• who receive antihistamine, topical steroid and systemic steroid > 20 mg/day within 7 days prior study

Trial design

Primary purpose: Diagnostic

Allocation: N/A

Interventional model: Single Group Assignment

Masking: None (Open label)

---

15 participants in 1 patient group

Atopy patch test

Experimental group

Description:

Atopy patches were applied on healthy volunteer's back for 48 hrs then the patches were removed. Reaction was evaluated 48 and 72 hrs after applying atopy patch test

Treatment:

Device: Atopy patch test with food allergen