Atrial and Ventricular Wall Stress During Breathing

Umeå University

Status: Completed

Conditions: Healthy

Treatments: Other: Simple breathing manuevers during brief echocardiographic imaging

Study type: Interventional

Funder types: Other

Identifiers

NCT03436030

2017-327-31M

Details and patient eligibility

About

Healthy reclining adult volunteers, with Valsalva manoeuver, Muller manoeuver, light continuous positive airway pressure by mask, passive leg raising, and maximal hand-grip. Ultrasound heart images captured before and during.

Full description

With focus on atrial wall strain and strain-rate, In healthy volunteer adult subjects, heart ultrasound is recorded during resting, Valsalva manoeuver, Muller manoeuver, passive leg raising, and handgrip. Echocardiographic recordings are made before and during each intervention. Participants are otherwise resting in a reclined position.

Enrollment: 40 patients

Sex: All

Ages: 18 to 70 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• healthy adults

Exclusion criteria

• known heart or lung disease

Trial design

Primary purpose: Diagnostic

Allocation: N/A

Interventional model: Single Group Assignment

Masking: None (Open label)

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40 participants in 1 patient group

Single arm, breathing manuevers

Experimental group

Description:

All subjects perform/undergo Valsalva, Muller, CPAP, hand grip, and passive leg raise, with ultrasound examination of heart recorded before and during the manoeuvre.

Treatment:

Other: Simple breathing manuevers during brief echocardiographic imaging