Atrial Fibrillation in Beta-Thalassemia

University Hospital of Ferrara

Status: Enrolling

Conditions: Atrial Fibrillation; Thalassemia

Study type: Observational

Funder types: Other

Identifiers

NCT05508932

419/2022/Oss/AOUFe

Details and patient eligibility

About

The study aims to evaluate the clinical, laboratory and instrumental differences that exist between beta-thalassemia patients with atrial fibrillation and those not affected by arrhythmia.

Full description

Observational, retrospective and prospective, single-center study, which involves the collection of clinical, laboratory, electrocardiographic and imaging data of patients with major or intermediate thalassemia who have performed, from 2012 to 2022, or will perform in the next 10 years, a cardiological evaluation at the Cardiology Unit of the University Hospital of Ferrara. Patients will be divided into two groups: thalassemia patients with atrial fibrillation (paroxysmal, persistent or permanent) and thalassemia patients with no history of atrial fibrillation.

The objective of the study is to evaluate whether there is a different prevalence of the characteristics analyzed among these patient populations.

Enrollment: 350 estimated patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

1. Transfusion-dependent Beta-thalassemia;
2. Follow-Up at the Cardiology Unit of the University Hospital of Ferrara;
3. Electrocardiogram performed;
4. Echocardiogram performed.

Exclusion criteria

1. Age <18 years;
2. State Of pregnancy;
3. Inability to give informed consent.

Trial design

350 participants in 1 patient group

Beta-thalassemia

Description:

Patients with Beta-thalassemia undergoing a cardiological evaluation