Atrificial Shrinkage of Blastocyst Before In Vitro Fertilization

Aljazeera Hospital

Status: Completed

Conditions: Infertility

Treatments: Device: ICSI with micro needle technique; Device: ICSI with laser pulse

Study type: Interventional

Funder types: Other

Identifiers

NCT04125017

blastocyst preparation

Details and patient eligibility

About

Vitrification is a modern cryopreservation technique based on sudden cooling of reproductive cells to a temperature of -196 ° C in seconds that produces glass-like solidification of a solution without crystallization, but by extreme elevation in viscosity during freezing

Full description

Vitrification is a modern cryopreservation technique based on sudden cooling of reproductive cells to a temperature of -196 ° C in seconds that produces glass-like solidification of a solution without crystallization, but by extreme elevation in viscosity during freezing Unlike the slow freezing method, vitrification has better results in a complete elimination of ice crystal inside the cells as well as in the surrounding solution -Also, it has a significantly higher post-thawing survival rate in comparison to slow freezing method

Enrollment: 409 patients

Sex: Female

Ages: 20 to 44 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• women with infertility from 20 to 44 years

Exclusion criteria

• women with age more than 44 or less than 20

Trial design

Primary purpose: Supportive Care

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Quadruple Blind

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409 participants in 2 patient groups

effect of using LASER pulse

Other group

Description:

effect of using LASER pulse versus micro-needle use in the artificial shrinkage of blastocysts as a previous step before vitrification in regarding their effect on embryo viability

Treatment:

Device: ICSI with laser pulse

Device: ICSI with micro needle technique

Micro-needle Technique

Other group

Description:

effect of using LASER pulse versus micro-needle use in the artificial shrinkage of blastocysts as a previous step before vitrification in regarding their effect on embryo viability

Treatment:

Device: ICSI with laser pulse

Device: ICSI with micro needle technique