Atropine Weight and Risk of Postoperative Confusion in the Elderly (ATROPAGE)

Toulouse University Hospital

Status: Unknown

Conditions: Aging

Treatments: Other: Data collection

Study type: Observational

Funder types: Other

Identifiers

NCT03390751

RC31/17/0202

2017-A01847-46 (Registry Identifier)

Details and patient eligibility

About

The identification of a high atropine load of treatment received during hospitalization as a predictor of postoperative confusion could have various benefits:

• Pharmacoepidemiological: identify factors associated with postoperative confusion
• Clinics: by favoring treatments with a low atropine load during anesthesia, the management of patients hospitalized in orthopedics. Similarly, stopping or re-evaluating treatments with a high atropine weight for scheduled surgery is an easy step to take.
• Socio-economic: by reducing the costs related to the occurrence of a confusional syndrome (over-treatment, prolonged hospital stay, loss of autonomy, institutionalization of patients...).

In total, the present study would improve the daily management of hospitalized patients and the practices of clinicians, by offering a decision-making aid.

Enrollment: 130 estimated patients

Sex: All

Ages: 65+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Admitted to the orthopedic department for surgical management of a fracture of the upper end of the femur in emergency or for the installation of a hip or knee prosthesis
• Patient able to understand and respond to the protocol
• No opposition to the collection of data of the patient or his / her designee

Exclusion criteria

• Pre-existing confusion to surgery, detected by the CAM scale
• Serious or moderate head trauma less than three months old
• Removing / installing prosthesis.

Trial design

130 participants in 1 patient group

Aged patients

Description:

Data collection of patients admitted to the orthopedic department of the University Hospital of Toulouse for surgical management of a fracture of the upper end of the femur in emergency or for the installation of a hip or knee prosthesis.

Treatment:

Other: Data collection