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Attention Bias Modification Treatment for Young Adults With Major Depressive Disorder

H

Hunan Normal University

Status

Completed

Conditions

Depressive Disorder, Major

Treatments

Behavioral: Attention bias modification

Study type

Interventional

Funder types

Other

Identifiers

NCT03971903
BBA130016

Details and patient eligibility

About

In this study, the investigators test whether a 4-week 12-session attention bias modification treatment (ABMT) could reduce depressive symptoms relative to placebo controls in young adults with major depressive disorder at post-training and 3-month follow-ups. Meanwhile, the investigators also test whether a 2-week 4-session ABMT booster training for every three months could reduce residual depressive symptoms and recurrences relative to placebo controls for 1-year follow-up

Full description

Attention Bias Modification Training was a modified dot-probe task, in which 90% of the targets appeared at the neutral word position and 10% at the sad word position. The placebo training procedure is a classic dot-probe task in which the targets appeared with equal probability in the sad (50%) and neutral (50%) word positions. The investigators assess attention bias scores, depressive symptoms, trait anxiety, rumination and self-report attention control ability at 1-week, 2-week, 4-week,7-week,3-month,4-month, 5-month, 6-month and 12-month follow-ups after training.

Enrollment

30 patients

Sex

All

Ages

16 to 20 years old

Volunteers

No Healthy Volunteers

Inclusion criteria

  • The presence of definite and probable MDD (i.e., at least 1 core symptom plus 3 further depressive symptoms present for at least 2 weeks) diagnoses

Exclusion criteria

  • a diagnosis of bipolar disorder, schizophrenia, or mood disorder due to a general medical condition or substance-induced mood disorder; and any concurrent treatment (i.e., psychotherapy and/or pharmacotherapy).

Trial design

Primary purpose

Treatment

Allocation

Randomized

Interventional model

Parallel Assignment

Masking

Triple Blind

30 participants in 2 patient groups, including a placebo group

Attention bias modification treatment
Experimental group
Description:
12-session of ABMT
Treatment:
Behavioral: Attention bias modification
Placebo controls
Placebo Comparator group
Description:
12-session of placebo(i.e.,sham) training
Treatment:
Behavioral: Attention bias modification

Trial contacts and locations

1

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Data sourced from clinicaltrials.gov

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