Attention Retraining for Anxiety Disorder Patients Resistent to Antidepressants

Hospital de Clinicas de Porto Alegre

Status: Unknown

Conditions: Panic Disorder; Generalized Anxiety Disorder; Social Anxiety Disorder

Treatments: Other: Attentional Bias Modification Treatment (ABMT) - Active; Other: Attentional Bias Modification Treatment - Placebo

Study type: Interventional

Funder types: Other

Identifiers

NCT01906268

13-0338

Details and patient eligibility

About

The objective of this project is to test the combination of active or placebo Attentional Bias Modification Treatment (ABMT) to usual treatment for anxiety disorder patients resistant to antidepressants.

Enrollment: 60 estimated patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Primary diagnosis of Generalized Anxiety Disorder, Panic Disorder or Social Anxiety Disorder according to the International Neuropsychiatric Interview psychiatric interview (M.I.N.I.)
• Current treatment for the anxiety disorder with antidepressants with an appropriate dose for at least 8 weeks;
• Score on OASIS (Overall Anxiety Severity and Impairment Scale)equal or greater than 8

Exclusion criteria

• Other psychiatric disorder that causes more impairment and suffering than generalized anxiety disorder, panic disorder or social anxiety disorder in the clinical evaluation
• Current Cognitive Behavior Therapy
• Marked intellectual disability (clinically evident)
• Suicidal ideation or suicide plan at the time of assessment(M.I.N.I.)
• Psychotic disorder (M.I.N.I.)
• Bipolar disorder type I (M.I.N.I.)
• Abuse / Dependence substances (M.I.N.I.)

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Quadruple Blind

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60 participants in 2 patient groups

TAU + ABMT active

Experimental group

Description:

Treatment as usual (TAU): selective serotonin reuptake inhibitor or serotonin-noradrenaline reuptake inhibitor Attention Bias Modification Treatment (ABMT) - active

Treatment:

Other: Attentional Bias Modification Treatment (ABMT) - Active

TAU + AMBT placebo

Sham Comparator group

Description:

Treatment as usual (TAU): selective serotonin reuptake inhibitor or serotonin norepinephrine reuptake inhibitor Attention Bias Modification Treatment (ABMT) - placebo (sham)

Treatment:

Other: Attentional Bias Modification Treatment - Placebo