Audio-enhanced Analgesia in Healthy Subjects

Mass General Brigham

Status: Completed

Conditions: Healthy

Treatments: Behavioral: Enhanced Audio; Behavioral: Audio

Study type: Interventional

Funder types: Other

Identifiers

NCT01835275

2012P000969

Details and patient eligibility

About

The purpose of this study is to determine whether enhanced audio methods can be used to improve analgesia for experimental pain in healthy subjects.

Enrollment: 60 patients

Sex: All

Ages: 18 to 50 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• 18-50 years old
• Healthy

Exclusion criteria

• Current diagnoses of psychiatric or neurological disorders or chronic pain
• BDI-II score greater than 13
• current or previous ear/nose/throat or hearing issues
• prior participation in pain studies
• previous advanced music training

Trial design

Primary purpose: Basic Science

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Single Blind

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60 participants in 3 patient groups

Music conditioning

Experimental group

Description:

Subjects are tested with music, sound, and silence, after conditioning to enhance music induced analgesia

Treatment:

Behavioral: Audio

Behavioral: Enhanced Audio

Sound

Active Comparator group

Description:

Subjects are tested with music, sound, and silence, after conditioning to enhance sound induced analgesia

Treatment:

Behavioral: Audio

Behavioral: Enhanced Audio

Calibration

No Intervention group

Description:

Subjects are tested with music, sound, and silence, with no enhanced audio received