Auditory and Visual Noise as Possible Non-pharmacological Treatment of ADHD in School Children

Region Skane

Status: Completed

Conditions: Attention Deficit Hyperactivity Disorder; Neurodevelopmental Disorders

Treatments: Device: Visual noise stimulation; Device: Auditory noise stimulation

Study type: Interventional

Funder types: Other

Identifiers

NCT06057441

2023-02476-01

Details and patient eligibility

About

The goal of this study is to compare the influence of visual and auditory white noise on performance in children with attention deficit hyperactivity disorder (ADHD). The main questions it aims to answer are:

• Can auditory white noise stimulation affect cognitive performance?
• Can visual white pixel noise affect cognitive performance? Participants will complete two eye tracking tasks under different sensory noise stimulation.

Researchers will compare the ADHD group with a group of typically developing children to see if the noise influences the groups differently and if it has the potential to affect the performance of the ADHD group, to reach the level of the control group.

Full description

Attention Deficit Hyperactivity disorder (ADHD) is one of the most frequent childhood disorders with an estimated prevalence of about 5%. Multimodal treatment is recommended in both national and international guidelines of ADHD care, but most patients only receive pharmacological treatment, sometimes in combination with parent training. As such, the most common treatment approach today is stimulant medication, e.g., methylphenidate. However, there are insufficient understanding about several aspects of medical treatment. For example, it is not evident that medication improves learning processes and the best dosage for cognitive functioning and adapted school behavior differs.

Original findings from our research group shows that auditory noise has the possibility of enhancing cognitive performance in inattentive children without diagnosis as well as children with an ADHD diagnosis. One study found that the benefit of noise was in parity with, or even larger than, the benefit of pharmacological ADHD treatment on two cognitive tasks. The theory about noise benefit is thoroughly described by Sikström and Söderlund (2007). If auditory or visual noise, as suggested by the present project, could be a complement, or an alternative, to stimulant medication it could fundamentally change the treatment of ADHD and the school situation for those children.

The aims of this study are to: i) evaluate the effects of auditory white noise and visual white pixel noise on cognitive performance during two eye tracking tasks, ii) compare effects between ADHD and control groups ii) link noise benefit to specific traits.

Enrollment: 60 patients

Sex: All

Ages: 8 to 17 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Children and adolescents with a diagnosis of ADHD and control children without a diagnosis

Exclusion criteria

• Intellectual disability
• Psychosis
• Severe depression or anxiety
• The need of an interpreter to participate in the study

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Crossover Assignment

Masking: None (Open label)

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60 participants in 4 patient groups

No noise stimulation

No Intervention group

Description:

A prolonged fixation (PF) task and memory guided saccade (MGS) task will be performed without noise.

Auditory white noise stimulation

Active Comparator group

Description:

A prolonged fixation (PF) task and memory guided saccade (MGS) task will be performed in auditory white noise.

Treatment:

Device: Auditory noise stimulation

Visual white pixel noise, 25%

Active Comparator group

Description:

A prolonged fixation (PF) task and memory guided saccade (MGS) task will be performed in visual white pixel noise at 25%.

Treatment:

Device: Visual noise stimulation

Visual white pixel noise, 50%

Active Comparator group

Description:

A prolonged fixation (PF) task and memory guided saccade (MGS) task will be performed in visual white pixel noise at 50%.

Treatment:

Device: Visual noise stimulation