Augmentation of Maxillary Horizontal And Vertical Bone Deficiency Using Mineralized Plasmatic Matrix

Cairo University (CU)

Status: Unknown

Conditions: Alveolar Ridge Abnormality of Maxilla

Treatments: Procedure: Augmentation

Study type: Interventional

Funder types: Other

Identifiers

NCT03757195

CEBC-CU-2017-11-16

Details and patient eligibility

About

A new technique of grafting introduce called Mineralized plasmatic matrix. This technique can be used in grafting in anterior zone giving a good results and bone substitution occur using allograft or xenograft.

The bone graft have a good consistency when it mixed with plasma give easy application, strength and stability of the graft. Also plasma rich with CGF (Cellular growth factors).

Full description

Patients suffering from anterior maxillary vertical and horizontal bone loss will be treated using a xeno-graft mixed with the same patient plasma that extracted from his own blood during the operation this graft will be stabilized by collagen membrane and surgical tags.

Patients will be follow up for 6 months to measure amount of bone loss of the xeno-graft during this period post operative using C.B.C.T

Enrollment: 28 estimated patients

Sex: All

Ages: 20 to 40 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Age: from 20 to 40 years old
• no history of previous grafting.
• no History of previous implant placement
• Medically Free e.g no debilitating diseases

Exclusion criteria

• Smoker patients.
• Alcoholic patients
• Pregnant.
• Drug Abusers.
• Hypertensive , Diabetic, having Problems or disease in Kidney and/or liver.
• Thyroid Disease.
• Problem in Vit.D absorption or in calcitonin hormone secretion.
• History of blood transfusion or donating blood less than 4 months.
• Patient under Corticosteroid therapy.
• Neurologicaly unstable patients.
• History of radiotherapy or chemo-therapy.
• Patient undergo Spect C.T Scan less than 4 Months .

Trial design

Primary purpose: Treatment

Allocation: N/A

Interventional model: Single Group Assignment

Masking: None (Open label)

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28 participants in 1 patient group

augmentation by xenograft

Experimental group

Description:

xenograft mixed with plasma extracted from blood

Treatment:

Procedure: Augmentation