Auricular Acupressure (AA) For Overweight/Obese Adolescent and Young Polycystic Ovary Syndrome ( PCOS)

Heilongjiang University of Chinese Medicine

Status: Unknown

Conditions: Polycystic Ovary Syndrome

Treatments: Other: Placebo auricular acupressure; Other: Auricular acupressure

Study type: Interventional

Funder types: Other

Identifiers

NCT02326714

AA for PCOS

Details and patient eligibility

About

The purpose of this trial is to investigate the effect and safety of auricular acupressure on adolescent and young women with PCOS. Subjects will be randomly assigned in to two arms: Auricular acupressure arm and placebo auricular acupressure, both arms will be treated for three months. Body mass index, oral glucose tolerance test, hormonal profile and metabolic profile will be determined.

Enrollment: 120 estimated patients

Sex: Female

Ages: 12 to 25 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Women aged between 12 and 25 years.
• Diagnosis of PCOS according to the modified Rotterdam criteria.
• 2 years after menarche.
• Body mass index (BMI) equal to or greater than 23 kg/m*m.

Exclusion criteria

• Administration of other medications known to affect reproductive function or metabolism within the past three months, including oral contraceptives, Gonadotropin-releasing hormone (GnRH) agonists and antagonists, anti androgens, gonadotropins, anti-obesity drugs, Chinese herbal medicines, anti diabetic drugs such as metformin and thiazolidinediones, somatostatin, diazoxide, and calcium channel blockers.
• Patients with other endocrine disorders including 21-hydroxylase deficiency, hyperprolactinemia, uncorrected thyroid disease, suspected Cushing's syndrome.
• Patients with known severe organ dysfunction or mental illness.

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Triple Blind

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120 participants in 2 patient groups, including a placebo group

Auricular acupressure

Experimental group

Description:

The magnetic beads will be taped to the seven pressing points: Hunger point, Ovary, Uterus, Endocrine point, liver, kidney and spleen.

Treatment:

Other: Auricular acupressure

Placebo auricular acupressure

Placebo Comparator group

Description:

The magnetic beads will be taped to the three pressing points:Tonsil, eye and elbow.

Treatment:

Other: Placebo auricular acupressure