Australian Trial in Acute Hepatitis C Recall Study (ATAHC Recall)

Kirby Institute

Status: Completed

Conditions: Acute Hepatitis C

Study type: Observational

Funder types: Other

Identifiers

NCT02000063

VHCRP1105 (Other Identifier)

Details and patient eligibility

About

A single long-term follow up assessment of an established multi-centre, prospective longitudinal cohort study of patients for clinical, psychosocial, immunovirological outcomes 4 to 8 years after previous treatment for recently acquired hepatitis C virus infection.

Full description

The study aims are:

1. To evaluate the effect of successful prior treatment or spontaneous clearance of recently acquired HCV infection on long-term quality of life, social functioning, injecting behaviour, mental health and liver health.
2. To assess the incidence of HCV re-infection following prior treatment induced clearance or spontaneous clearance of recently acquired chronic HCV infection.
3. To determine predictors of HCV re-infection following recently acquired HCV infection treatment.
4. To determine frequency and predictors of new mixed and superinfections in ATAHC subjects with persistent viraemia.
5. To add to a tissue repository of serum and PBMCs from well-characterised patients treated for recently acquired HCV infection to allow future examination of the role of other variables that may potentially impact on the prognosis and outcomes of early HCV treatment.

Enrollment: 50 patients

Sex: All

Ages: 16+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Previous enrolment in the Australian Trial of Acute Hepatitis C Virus Infection (ATAHC) Study.
• Provision of written, informed consent.

Exclusion criteria

• In the opinion of the investigator that the patient is not able to provide informed consent.
• Inability or unwillingness to comply with study collection requirements.