Autoantibodies Against Specific Cytokines in Adults With Severe Mycobacterial Infection

China Medical University

Status: Unknown

Conditions: Mycobacterium Infection

Study type: Observational

Funder types: Other

Identifiers

NCT01628744

DMR-99-IRB-075-1

Details and patient eligibility

About

In adult, the prevalence of mycobacterial infections is increased with age is largely unknown. IFN-gamma-IL-12/23 axis or NF-kappaB pathways might also plays crucial roles in adult against mycobacteria. Based on this hypothesis, the investigators had applied a functional assay to these pathways in patients with mycobacterial infection.

Enrollment: 100 estimated patients

Sex: All

Volunteers: No Healthy Volunteers

Inclusion criteria

• Patients with mycobacterial infection

Exclusion criteria

• Malignancy
• Severe autoimmune
• HIV infection

Trial design

100 participants in 1 patient group

Patients with mycobacterial infection