Autobiographical Specificity (ESAD)

Nantes University Hospital (NUH)

Status: Enrolling

Conditions: Alzheimer Disease; Frontotemporal Dementia; Memory

Treatments: Other: Autobiographical reminder

Study type: Observational

Funder types: Other

Identifiers

NCT05642351

RC22_0626

Details and patient eligibility

About

Autobiographical memory is diminished in patients with Alzheimer's Disease and those with behavioral variant of frontotemporal dementia, and research has focused on the hampered ability of patients in retrieving specific memories. However, this study proposes a detailed methodology to provide a qualitative analysis of autobiographical specificity.

Full description

Patients with Alzheimer's Disease and those with behavioral variant of frontotemporal dementia will be invited to retrieve autobiographical memories. Memories will be analyzed and categorized into specific, categoric, extended, or semantic autobiographical retrieval.

Enrollment: 62 estimated patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Alzheimer' disease or avioral variant of frontotemporal dementia
• No opposition from the patient to be included in the study
• For Alzheimer's patients: a score of more than 24 out of 30 on the Mini Mental State Examination (McKhann et al., 1984)

Exclusion criteria

• Other psychiatric/neurological disorders
• Minor patients
• Adults under guardianship or protection.

Trial design

62 participants in 2 patient groups

Alzheimer's Disease

Description:

recruited according to criteria by National Institute on Aging (McKhann et al., 2011).

Treatment:

Other: Autobiographical reminder

Behavioral variant of frontotemporal dementia

Description:

recruited following criteria by Rascovsky et al. (2011)

Treatment:

Other: Autobiographical reminder