Autogenous Bone Mixed With Xenograft Versus Xenograft Alone Versus Absorbent Gelatin Sponge

Cairo University (CU)

Status: Unknown

Conditions: Bone Graft Failure; Alveolar Bone Loss; Alveolar Bone Resorption; Bone Resorption

Treatments: Procedure: Mixture of Autogenous bone & Anorganic Bovine Bone (ABB); Procedure: Absorbable gelatin sponge; Procedure: Anorganic Bovine Bone (ABB)

Study type: Interventional

Funder types: Other

Identifiers

NCT03584984

2807

Details and patient eligibility

About

Alveolar bone atrophy post-extraction has been well documented in the past years. normal healing event results in a minimal loss of vertical height (around 1 mm), but a substantial loss of width in the buccal-lingual plane (4-6 mm). Alveolar socket preservation is thought to deal with this issue as to prevent the loss of alveolar bone dimensions post extraction in the case of delayed implant placement

Enrollment: 30 estimated patients

Sex: All

Ages: 18 to 50 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Adult patients with hopeless mandibular molars indicated for extraction and implant placement in two stages that indicate socket preservation.
• Both sexes.
• No intraoral soft and hard tissue pathology.
• No systemic condition that contraindicate implant placement.

Exclusion criteria

• Presence of fenestrations or dehiscence of the residual bony Walls after extraction.
• Heavy smokers more than 20 cigarettes per day .(24)
• Patients with systemic disease that may affect normal healing.
• Psychiatric problems
• Disorders to implant are related to a history of radiation therapy to the head and neck neoplasia, or bone augmentation to implant site.
• Patients that refuse to be called back for implant placement post extraction.
• Patients that have exceeded bone resorption surrounding the tooth prior to extraction and require guided bone regeneration.
• Pregnant Females.

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Quadruple Blind

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30 participants in 3 patient groups

Mixture of Autogenous bone & Anorganic Bovine Bone (ABB)

Experimental group

Description:

socket preservation with a mixture of autogenous bone graft acquired at the time of extraction mixed with a 50:50 ratio of Anorganic bovine bone

Treatment:

Procedure: Mixture of Autogenous bone & Anorganic Bovine Bone (ABB)

Anorganic bovine bone graft (ABB)

Active Comparator group

Description:

filling the extraction socket with ABB graft

Treatment:

Procedure: Anorganic Bovine Bone (ABB)

Absorbable gelatin Sponge

Active Comparator group

Description:

Filling the socket with an absorbable gelatin sponge

Treatment:

Procedure: Absorbable gelatin sponge