Autogenous Tooth Bone Graft for Alveolar Socket Preservation (ATBG)

Haifaa Mohammed Al-hussini

Status: Active, not recruiting

Conditions: Tooth Extraction Site Healing; Bone Regeneration Following Wisdom Teeth Extraction; Alveolar Bone Grafting

Treatments: Biological: "Autogenous Tooth Bone Graft"

Study type: Interventional

Funder types: Other

Identifiers

NCT07267637

SU-DENT-ATBG-2025-HH

Details and patient eligibility

About

The purpose of this clinical experiment is to assess how well autogenous tooth bone grafting preserves the alveolar socket after surgical tooth extraction. Before being inserted into the socket, the graft is made from the patient's own extracted tooth and ground into a particle. Twenty Yemeni patients who needed their teeth extracted are included in the trial, and they will be followed up with clinical and radiographic procedures using cone-beam computed tomography (CBCT) for six months. The primary objective is to ascertain whether the autogenous dental bone graft can preserve the height, width, and density of alveolar bone, offering a secure, affordable, and biocompatible substitute for traditional grafting materials.

Full description

This interventional clinical study investigates the role of autogenous tooth bone graft in alveolar socket preservation after surgical tooth extraction. The extracted tooth is cleaned, dried, processed into particulate graft material manually using bone crusher, and disinfect and treated using (NaOH) and (Na CL). The graft particles are immediately placed into the fresh extraction socket and sutured. Twenty Yemeni patients requiring impacted lower third molar and upper canine teeth surgical extractions will be included. The healing process will be evaluated both clinically and radiographically over a 6-month period. Cone-beam computed tomography (CBCT) scans will be used to assess bone density and alveolar ridge dimensions before extraction and at six months' post-intervention. The study aims to determine whether autogenous tooth bone grafts can effectively reduce post-extraction alveolar bone resorption and maintain ridge dimensions, supporting their potential use as an autologous, biocompatible, and economically feasible graft material for clinical socket preservation.

Enrollment: 20 patients

Sex: All

Ages: 18 to 40 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• - Absence of systemic diseases.
• Very good to accepted oral hygiene.
• Patients with impacted teeth requiring extraction.
• Patients between the ages of 16 and 50.
• No history of smoking.
• No history of any other drug use.
• Patients who were cooperative, motivated, to attend the follow-up and maintenance visits.

Exclusion criteria

• Systemic conditions or pharmacological therapies that could be an absolute contraindication for the intervention (such as un controlled diabetics, immunocompromised states, or treatment with oral or parenteral bisphosphonates).
• Poor oral hygiene.
• Acute exacerbation of chronic infection like pain or swelling.
• Pregnant women, children, elderly (>60 years), physically and mentally challenged, terminally and seriously ill.
• Hight Smoking tendency.
• Patients who refused to participate in the trial.
• Uncooperative Patients who won't be able to maintain the follow up visits

Trial design

Primary purpose: Treatment

Allocation: N/A

Interventional model: Single Group Assignment

Masking: None (Open label)

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20 participants in 1 patient group

Autogenous Tooth Bone Graft Intervention Group

Experimental group

Description:

"In this arm of the study, participants will receive an autogenous tooth bone graft for alveolar socket preservation following surgical tooth extraction. The intervention involves the extraction of the patient's own tooth, which will be processed and used as a bone graft. This graft will be placed into the empty socket immediately after the extraction. The purpose of this intervention is to prevent bone resorption, promote natural healing, and support bone regeneration within the extraction site. CBCT scans will be performed before extraction to measure baseline bone dimensions and will be repeated 6 months post-intervention to assess the success of bone preservation in terms of height, width, and density."

Treatment:

Biological: "Autogenous Tooth Bone Graft"