Autologous Bone Marrow Stem Cell Transplantation in Patients With Spinal Cord Injury

Hospital Sao Rafael

Status: Completed

Conditions: Spinal Cord Injury

Treatments: Procedure: Stem Cell Transplantation

Study type: Interventional

Funder types: Other; NETWORK

Identifiers

NCT01325103

SCI-001

Details and patient eligibility

About

This research investigates the use of autologous bone marrow stem cells in patients with spinal cord injury.

Full description

The aim of this study is to evaluate autologous bone marrow stem cells transplantation as a safe and potentially beneficial treatment for patients with spinal cord injury.

Enrollment: 14 patients

Sex: All

Ages: 18 to 50 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Age between 18 and 50 years old
• Traumatic spinal cord injury at the thoracic or lumbar level
• Classification Frankel A
• Indication for spinal surgery for traumatic lesions of bone

Exclusion criteria

• Section of the spinal anatomy
• Open injuries
• Active infectious diseases
• Terminal patients
• Neurodegenerative diseases
• Primary hematologic diseases
• Bone reflecting increased risk for spinal puncture
• Coagulopathies
• Hepatic dysfunction
• Pregnancy
• Other medical complications that contraindicate surgery, including major respiratory complications
• Participation in another clinical trial
• Use of metal implants close to vascular structures (such as cardiac pacemaker or prosthesis) that contraindicate MRI

Trial design

Primary purpose: Treatment

Allocation: N/A

Interventional model: Single Group Assignment

Masking: None (Open label)

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14 participants in 1 patient group

Stem Cell Transplantation

Experimental group

Description:

Patients with spinal cord injury that will undergo autologous bone marrow stem cell transplantation.

Treatment:

Procedure: Stem Cell Transplantation