Autologous Cellular Therapy With PRP-PC in Chronic Lung Diseases: An Observational Study LI-004

H-CYTE

Status

Completed

Conditions

COPD ILD

Treatments

Biological: Autologous Cellular Therapy with PRP-PC

Study type

Observational

Funder types

Industry

Identifiers

NCT05562843

HCYTE LI-004

Details and patient eligibility

About

For this study, cells will be harvested from the patient from the peripheral blood, isolated and concentrated using proprietary Emcyte™ equipment/centrifugation, and then returned to the patient same day via the peripheral circulation. As circulation occurs, the concentrated cells enter the right heart and are then disseminated into the lungs, becoming trapped in the lung's microcirculation. Here, the cells are believed to produce multiple bioactive factors such as cytokines and anti-inflammatory mediators. Several growth factors are released by activated platelets becoming honing cells for healing within the tissue. The exact long-term mechanism of action of PRP-PC in the lungs remains under investigation. Safety studies have proven that autologous treatment is incredibly safe, largely because of the minimal cell manipulation and the autologous nature of the cells. Prior observational studies in this are have shown strong safety profiles as well as strong efficacy in both COPD and ILD.

Full description

Study Objective(s) Primary

To determine if pulmonary function improves following ceullar therapy Secondary
To determine if participants' perceived quality of life related to breathing improves following cellular therapy To evaluate the safety of autologous PRP-PC administration for chronic lung disease

Enrollment

150 patients

Sex

All

Ages

18+ years old

Volunteers

No Healthy Volunteers

Inclusion criteria