Autologous Fat Grafting With PRP (Platelet Rich Plasma) to Anophthalmic Sockets

Fox, Donald Munro, M.D., P.C.

Status: Completed

Conditions: Orbital Atrophy

Treatments: Procedure: autologous fat grafting with PRP to anophthalmic orbits

Study type: Interventional

Identifiers

NCT01712555

New York Eye and Ear Infirmary

Details and patient eligibility

About

After people lose an eye, for whatever reason, they often experience fat atrophy of the tissues in the orbit. This leads to a sunken appearance that is often not correctable by a cosmetic shell prosthesis. Current techniques to correct this deformity are inadequate/ invasive. Injection of various gels (Restylane, Radiesse) are temporary had have their own disadvantages. This study seeks to demonstrate an improvement in the retention of injected autologous fat by mixing in autologous PRP (platelet rich plasma).

Enrollment: 5 patients

Sex: All

Ages: 21 to 70 years old

Volunteers: Accepts Healthy Volunteers

Inclusion and exclusion criteria

Inclusion Criteria: anophthalmos, orbital atrophy -

Exclusion Criteria:poor anesthesia risk, people outside a 100 mile radius of New York City

Trial design

Primary purpose: Treatment

Allocation: N/A

Interventional model: Single Group Assignment

Masking: None (Open label)

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5 participants in 1 patient group

fat grafting with PRP to anophthalmic orbits

Experimental group

Description:

There is only one arm to this study. People with orbital atrophy and loss of an eye are to be injected with autologous fat mixed with autologous PRP (platelet rich plasma) and observed for at least one year for evidence of retention of the injected fat

Treatment:

Procedure: autologous fat grafting with PRP to anophthalmic orbits