Autologous Nanofat Grafting by Injection Versus With Microneedling in Post-burn and Traumatic Atrophic Scars

Alexandria University

Status: Enrolling

Conditions: Scars

Treatments: Procedure: microneedling with autologus nanofat graft; Procedure: injection of autologous nanofat grafting

Study type: Interventional

Funder types: Other

Identifiers

NCT06566300

Nanofat scar

Details and patient eligibility

About

This study aims to evaluate the efficiency autologous nanofat injection versus autologous nanofat delivered by microneedling in management of post burn atrophic and traumatic scars.

Enrollment: 30 estimated patients

Sex: All

Ages: 18 to 60 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• 1. Males and females between 18-60 years old. 2. Post-burn or traumatic atrophic scar > 6 months duration (16). 3. Patients not receiving any treatments for the scar within the past 3 months.

Exclusion criteria

• 1. Patients with contractures, hypertrophic and keloid scars. 2. Patients with history of bleeding disorders or coagulopathy, or on anticoagulant therpy.

  2. Diabetes and other systemic diseases that may be complicated by the procedure.

  3. Pregnant and lactating females. 5. BMI less than 18.5 6. Patients with scars at the donor site

Trial design

Primary purpose: Treatment

Allocation: Non-Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

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30 participants in 2 patient groups

injection of autologous nanofat grafting

Experimental group

Description:

Two separate scars with similar properties or splitting of one large post-burn atrophic scar. One (part of the) scar will be treated by injection of autologous nanofat grafting and the other (part of the) scar will be treated by microneedling with autologous nanofat graft.

Treatment:

Procedure: injection of autologous nanofat grafting

microneedling with autologous nanofat graft

Experimental group

Description:

Two separate scars with similar properties or splitting of one large post-burn atrophic scar. One (part of the) scar will be treated by injection of autologous nanofat grafting and the other (part of the) scar will be treated by microneedling with autologous nanofat graft.

Treatment:

Procedure: microneedling with autologus nanofat graft