Autologous Prefabrication of Body Surface Tissues/ Organs(e.g. Joint)

Shanghai Jiao Tong University School of Medicine

Status

Unknown

Conditions

Intentional Self Harm by Other Specified Means

Soft Tissue Infections

Treatments

Procedure: tissue/ organ prefabrication

Study type

Interventional

Funder types

Other

Identifiers

NCT02595047

[2012]23

Details and patient eligibility

About

The purpose of this study is to observe the feasibility and its application of autologous prefabrication for body surface tissues/oranges

Full description

In the field of tissue regeneration techniques, the in vitro processes and other exogenous factors still have many uncertainties. These uncertainties have hampered road to the clinical application. As the importance of in vivo environment has aroused more awareness, the investigators validated the hypothesis that the feasibility of self-regeneration prefabricated unaided by any in vitro culture process or exogenous elements.

Enrollment

1 estimated patient

Sex

All

Ages

5 to 65 years old

Volunteers

Accepts Healthy Volunteers

Inclusion criteria

With body surface tissue or organ defects (e.g., ear, nose, bone and joint) requiring reconstruction.

Exclusion criteria

evidence of infection, ischemia, ulcer or other pathological changes within the prefabricated area which defined as not suitable for tissues regeneration
history of delayed healing, radiational therapy;
significant renal, cardiovascular, hepatic and psychiatric diseases;
significant medical diseases or infection (including but not limited to the carrier of hepatitis B virus or HIV);
BMI >30;
history of any hematological disease, including leukopenia, thrombocytopenia, or thrombocytosis;
Evidence of malignant diseases
unwillingness to participate.