Autologous Serum Skin Test and Serum IL-18 Levels in Chronic Idiopathic Urticaria and Respiratory Allergic Diseases

Eskisehir Osmangazi University

Status: Completed

Conditions: Urticaria; Respiratory Allergic Diseases

Treatments: Procedure: autologous serum skin test, serum IL-18

Study type: Observational

Funder types: Other

Identifiers

NCT01091402

1

Details and patient eligibility

About

One of the proposed mechanisms in CU is autoimmunity. It was shown by a positive response to autologous serum skin test (ASST)in almost half of chronic urticaria (CU) patients. IL-18 also play a role in autoimmune disorders. The investigators aim was to investigate the relationship of ASST and IL-18 in CU and respiratory allergic diseases.

Sex: All

Ages: 16+ years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• adult patients
• chronic urticaria patients
• stable asthma patients
• allergic rhinitis patients with sensitized to pollens
• normal controls without atopic and skin disease.

Exclusion criteria

• unwillingness to the study
• other dermatological problems that could affect the skin test
• use of antihistamine drugs

Trial design

0 participants in 4 patient groups

chronic urticaria

Treatment:

Procedure: autologous serum skin test, serum IL-18

asthma

Treatment:

Procedure: autologous serum skin test, serum IL-18

seasonal allergic rhinitis

Treatment:

Procedure: autologous serum skin test, serum IL-18

normal controls

Treatment:

Procedure: autologous serum skin test, serum IL-18