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Autologous Serum Skin Test and Serum IL-18 Levels in Chronic Idiopathic Urticaria and Respiratory Allergic Diseases

E

Eskisehir Osmangazi University

Status

Completed

Conditions

Urticaria
Respiratory Allergic Diseases

Treatments

Procedure: autologous serum skin test, serum IL-18

Study type

Observational

Funder types

Other

Identifiers

Details and patient eligibility

About

One of the proposed mechanisms in CU is autoimmunity. It was shown by a positive response to autologous serum skin test (ASST)in almost half of chronic urticaria (CU) patients. IL-18 also play a role in autoimmune disorders. The investigators aim was to investigate the relationship of ASST and IL-18 in CU and respiratory allergic diseases.

Sex

All

Ages

16+ years old

Volunteers

Accepts Healthy Volunteers

Inclusion criteria

  • adult patients
  • chronic urticaria patients
  • stable asthma patients
  • allergic rhinitis patients with sensitized to pollens
  • normal controls without atopic and skin disease.

Exclusion criteria

  • unwillingness to the study
  • other dermatological problems that could affect the skin test
  • use of antihistamine drugs

Trial design

0 participants in 4 patient groups

chronic urticaria
Treatment:
Procedure: autologous serum skin test, serum IL-18
asthma
Treatment:
Procedure: autologous serum skin test, serum IL-18
seasonal allergic rhinitis
Treatment:
Procedure: autologous serum skin test, serum IL-18
normal controls
Treatment:
Procedure: autologous serum skin test, serum IL-18

Trial contacts and locations

1

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Data sourced from clinicaltrials.gov

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