Autologous Serum Skin Testing in Patients With Atopic Dermatitis Autologous Serum Skin Testing in Patients With Atopic Dermatitis

Yuzuncu Yıl University

Status: Completed

Conditions: Atopic Dermatitis, Serum Skin Test

Study type: Observational

Funder types: Other

Identifiers

NCT01238263

yavuzyesilova

Details and patient eligibility

About

Recently, IgE-type autoantibodies against self proteins have been detected in the serum of the atopic dermatitis patients. The role of this IgE autoantibodies involved in the pathogenesis of atopic dermatitis is not known, yet. But, there may be a correlation between the severity of the disease and the serum levels of this autoantibodies. The autologous serum skin testing is applied to both atopic dermatitis patients and healthy control and the results are estimated in this study.The investigators detected 70% positive autologous serum skin testing in atopic dermatitis patients and test positivity was higher in patients with atopy history, moderately severe disease calculated by SCORAD index and high serum IgE levels.

Enrollment: 90 patients

Sex: All

Ages: 1 to 45 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Sixty AD patients and 30 healthy individuals

Exclusion criteria

• . The patients showing evidence of any other disease are not included to our study. No drug was allowed fourteen days prior to the test, including antihistamines and steroids.