Automated Bone Age Estimation From Noncontrast Abdominal CT Using Deep Learning

Peking University

Status: Enrolling

Conditions: Osteoporosis Diagnosis; Bone Aging

Study type: Observational

Funder types: Other

Identifiers

NCT07162168

2024PHB388-001

Details and patient eligibility

About

This study is a retrospective analysis that uses abdominal CT scans, which were originally taken for other medical reasons, to estimate bone age. By applying advanced deep learning methods, the investigators aim to develop a tool that can evaluate bone health and detect early signs of osteoporosis without requiring additional scans or radiation. This approach may help doctors better understand bone aging, improve screening for bone weakness, and provide patients with more personalized information about their bone health.

Enrollment: 3,000 estimated patients

Sex: All

Ages: 18+ years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Adults aged over 18 years.
• Underwent routine noncontrast abdominal CT scans.
• CT scans fully included the proximal femur.
• Scans were performed for non-orthopedic clinical indications.
• Provided necessary demographic information (e.g., age, sex).

Exclusion criteria

• CT scans with poor image quality or severe artifacts that precluded accurate analysis.
• History of hip surgery or presence of internal fixation devices.
• Presence of bone tumors in the proximal femur.
• Severe hip deformity or prior fractures affecting the proximal femur.
• Pediatric patients or pregnant individuals (if applicable).

Trial design

3,000 participants in 9 patient groups

Peking University People's Hospital cohort

Description:

No intervention

Shandong Cohort

Description:

No intervention

Canton Cohort

Description:

No intervention

Guizhou cohort

Description:

No intervention

Hunan Cohort

Description:

No intervention

Inner Mongolia Cohort

Description:

No intervention

Shaanxi Cohort

Description:

No intervention

Shandong Cohort2

Description:

No intervention

Other province Cohort

Description:

No intervention