Automated Quantification of Radiologic Pulmonary Alteration During Acute Respiratory Failure: Application to the COVID-19 Pandemic (QUANTICO-PRO)

University Hospital, Strasbourg, France

Status: Enrolling

Conditions: SARS-CoV-2 Infections; Respiratory Failure With Hypoxia

Treatments: Radiation: Thoracic CT scan

Study type: Interventional

Funder types: Other

Identifiers

NCT05278390

8138

Details and patient eligibility

About

Automated quantification of the pulmonary volume impaired during acute respiratory failure could be helpful to assess patient severity during COVID-19 infection or perioperative medicine, for example.

This study aims at assessing the correlation between the amount of radiologic pulmonary alteration and the clinical severity in two clinical situation :

1. SARS-CoV-2 infections
2. Postoperative hypoxemic acute respiratory failure.

Enrollment: 500 estimated patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Subject admitted to a care unit of the University Hospitals of Strasbourg or the University Hospital of Nancy and presenting a suspicion of SARS-CoV-2 infection or postoperative hypoxemic respiratory failure
• Able to understand the objectives and risks of the research and to give dated and signed informed consent.

Subjects may also be included in emergency or immediate life-threatening situations.

• Subject with insurance covering

Exclusion criteria

• Pregnant woman (pregnancy confirmed by a urine or blood test)
• Subject usually on home oxygen therapy
• Subject under court protection
• Subject under guardianship or curatorship

Trial design

Primary purpose: Diagnostic

Allocation: N/A

Interventional model: Single Group Assignment

Masking: None (Open label)

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500 participants in 1 patient group

Thoracic CT Scan

Experimental group

Treatment:

Radiation: Thoracic CT scan