Automatic Ventilation in Prehospital Resuscitation on OHCA

National Taiwan University

Status: Enrolling

Conditions: Out-Of-Hospital Cardiac Arrest

Treatments: Device: Manual ventilation; Device: Automatic ventilation

Study type: Interventional

Funder types: Other

Identifiers

NCT06067204

202304132RINB

Details and patient eligibility

About

The goal of this randomized controlled trial is to compare prehospital ventilation strategies in out-of-hospital cardiac arrest. The intervention group is automatic ventilation and the control group is manual ventilation. The main questions it aims to answer are:

1. How does automatic ventilation affect OHCA patients' survival and prognosis comparing to manual ventilation.
2. What are the differences on resuscitation qualities between automatic ventilation and manual ventilation.

Enrollment: 514 estimated patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Age over 18 years old at the time of occurrence of out-of-hospital cardiac arrest (OHCA).
• Attended by the Hsinchu County Fire Department for emergency medical assistance.

Exclusion criteria

• Pregnant women.
• OHCA caused by trauma.
• Return of spontaneous circulation (ROSC) observed at the scene.
• Clearly deceased at the scene (reaching conditions such as decomposition, rigor mortis, severe burns, decapitation, evisceration, or trunk fracture).
• Refusal of medical transportation by family members.
• No placement of an advanced airway throughout the procedure.

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Triple Blind

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514 participants in 2 patient groups

Automatic ventilation

Experimental group

Description:

After the advanced airway is placed, an automatic pneumatic ventilator will be connected and provides ventilation in every 6 seconds.

Treatment:

Device: Automatic ventilation

Manual ventilation

Active Comparator group

Description:

After the advanced airway is placed, a bag valve mask resuscitator will be connected and provides ventilation in every 6 seconds by the emergency medical technician.

Treatment:

Device: Manual ventilation