Autonomic and Metabolic Response to Cardiac Rehabilitation After Acute MI (RIABILITOMICA)

Istituto Auxologico Italiano

Status: Enrolling

Conditions: Acute Myocardial Infarction: Rehabilitation Phase

Treatments: Other: Cardiac rehabilitation

Study type: Observational

Funder types: Other

Identifiers

NCT06298513

09C338

Details and patient eligibility

About

Ischemic heart disease remains the leading cause of death in the western world. The beneficial effects of cardiac rehabilitation on the evolution of ischemic heart disease are known, but the effects of rehabilitation on the metabolic processes of the patients are so far poorly understood. Metabolomics is the qualitative/quantitative analysis of the body's metabolic responses to pathophysiological stimuli or genetic alterations. Metabolic changes caused by physical activity have been demonstrated in obese and diabetic patients and in athletes. Aim of the study is to evaluate whether cardiac rehabilitation after a first myocardial infarction induces changes in the metabolic state of patients, and whether these changes may be related with changes in the usual risk factors (i.e. glyco-lipidic profile, natriuretic peptides, homocysteine).

Enrollment: 25 estimated patients

Sex: Male

Ages: 25 to 75 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• recent first acute myocardial infarction

Exclusion criteria

• severe diabetes

Trial design

25 participants in 1 patient group

Patient after first acute myocardial infarction

Treatment:

Other: Cardiac rehabilitation