Autonomic Dysfunction and Inflammation in Chronic Hemodialysis Patients

Martin-Luther-Universität Halle-Wittenberg

Status: Completed

Conditions: Chronic Renal Failure; Autonomic Dysfunction

Study type: Observational

Funder types: Other

Identifiers

NCT00878033

UKH-KIMII-001-09

Details and patient eligibility

About

This study investigates the relationship between autonomic dysfunction and chronic inflammation in hemodialysis patients.

Enrollment: 45 patients

Sex: All

Ages: 18+ years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Chronic Kidney Disease Stadium KDIGO 5D for at leat 3 months on Dialysis
• Age >18 years
• Sinus action in EKG
• Patient capable for informed consent
• Written and signed informed consent

Exclusion criteria

• Clinical overt signs of infections of any kind
• Active malign disease
• CRP levels above 50 mg/L
• Cardiac Pace Maker
• Atrial Fibrillation
• Refusal of informed consent
• Cardiac Transplantation
• Immunosuppressive medication

Trial design

45 participants in 3 patient groups

1

Description:

Diabetic Dialysis Patients

2

Description:

Non-Diabetic Dialysis Patients

3

Description:

Healthy Controls