Autonomic Dysfunction in Patients With Pectus Excavatum. (ADPE)

Buddhist Tzu Chi Medical Foundation

Status: Unknown

Conditions: Surgery; Autonomic Dysfunction; Pectus Excavatum

Treatments: Procedure: Nuss surgery

Study type: Observational

Funder types: Other

Identifiers

NCT03346876

05-XD-57-110

TCRD-TPE-106-RT-2 (Other Grant/Funding Number)

Details and patient eligibility

About

Investigators conducted a pilot study to to evaluate the autonomic function in participants with pectus excavatum before and after Nuss surgery.

Full description

Since pectus excavatum can cause cardiac arrhythmia, the cardiac autonomic function in participants with pectus excavatum might be impaired. However, to our knowledge, there is no any study to evaluate the cardiac autonomic function in participants with pectus excavatum.

Enrollment: 120 estimated patients

Sex: All

Ages: 13 to 45 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

1. Clinical diagnosis of pectus excavatum
2. Agree to receive Nuss surgery to correct pectus excavatum

Exclusion criteria

1. Major medical disease (asthma, heart failure, renal disease)
2. Known psychiatric disease
3. Known sleep-disordered breathing
4. Skeletal disease
5. Major surgery within 6 months

Trial design

120 participants in 2 patient groups

Study group

Description:

patients with pectus excavatum

Treatment:

Procedure: Nuss surgery

Control group

Description:

healthy subjects without pectus excavatum