Autonomic Dysreflexia in Spinal Cord Injury

University of Aarhus

Status: Completed

Conditions: Spinal Cord Injured; Autonomic Dysfunction

Treatments: Procedure: bowel emptying

Study type: Interventional

Funder types: Other

Identifiers

NCT01059370

2009-0112

Details and patient eligibility

About

Autonomic dysreflexia in high spinal cord-injured can be initiated by a full bladder or bowel, or when trying to empty either. This randomised study aims at evaluating whether irrigation procedure or digital stimulation or evacuation of the rectum is less provocative of autonomic dysreflexia. Participants have their bowels emptied on different days, in the morning fasting. Bladder filling with sterile saline water is evaluated on a third day as a control.

Enrollment: 12 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

1. People with a spinal cord injury above th6 and with symptoms of autonomic dysreflexia.
2. At least one year post injury.
3. 18 years or older.
4. Informed consent.

Exclusion criteria

1. Usage of prophylactic anti-autonomic dysreflexia medication.
2. Pregnant or breastfeeding.
3. People who is not able to follow the sudy protocol.
4. No former major surgery in the abdomen or pelvic region.
5. No former radiotherapy in the pelvic region.

Trial design

Primary purpose: Prevention

Allocation: Randomized

Interventional model: Single Group Assignment

Masking: Single Blind

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12 participants in 1 patient group

Autonomic dysrefleksia

Experimental group

Description:

Autonomic dysreflexia in SCI when emptying bowels or filling bladder

Treatment:

Procedure: bowel emptying