AV Node Isolation in Atrial Fibrillation vs. Modulation by "Pace and Ablate" Strategy

Heart and Diabetes Center North-Rhine Westfalia

Status: Completed

Conditions: AV Node Ablation; Atrial Fibrillation; Escape; Rhythm

Treatments: Procedure: AV-node ablation; Procedure: AV-node isolation

Study type: Observational

Funder types: Other

Identifiers

NCT04859933

HDZ_ER_003_GI

Details and patient eligibility

About

AV-node ablation (AVNA) is a common therapy option for rate control strategy of permanent atrial fibrillation with numerous side effects. The investigators hypothesised that an isolation of the AV node is concomitant with less occurrence of new bundle brunch blocks, more frequent preservation and higher rate of escape rhythm compared to AVNA. This retrospective study includes 20 patients being treated with AV-node isolation (AVNI) and 40 historical AVNA-controls. Among others these two methods were compared regarding escape rhythm, delta QRS, procedure time, ablation points, fluoroscopy time and total dose area product (DAP).

Enrollment: 60 patients

Sex: All

Ages: 18 to 100 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• paroxysmal, persistend or permanent atrial fibrillation; indication for AVNA

Exclusion criteria

• other indications for AVNA than atrial fibrillation as AVNRT, atrial flutter, atrial tachycardia

Trial design

60 participants in 2 patient groups

AVNA group

Description:

Group of historical controls beeing treated with AV-node ablation

Treatment:

Procedure: AV-node ablation

AVNI group

Description:

Inculudes all patients beeing treated with AV-node isolation

Treatment:

Procedure: AV-node isolation