Avastin for Post-photocoagulation Macular Edema

Asociación para Evitar la Ceguera en México

Status and phase: Withdrawn; Phase 4

Conditions: Macular Edema

Treatments: Drug: Bevacizumab; Procedure: Panretinal Photocoagulation

Study type: Interventional

Funder types: Other

Identifiers

NCT00801866

APEC-035

Details and patient eligibility

About

to evaluate the efficacy of a single intravitreal bevacizumab (IVB) injection, 0.1mL (2.5mg), against panretinal photocoagulation (PRP)-induced macular thickening and visual disturbance in patients with severe nonproliferative diabetic retinopathy (NPDR) and proliferative diabetic retinopathy (PDR) and good vision

Sex: All

Ages: 15 to 80 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Patients with Proliferative retinopathy or severe non-proliferative retinopathy
• BCVA of 20/63 or better (56 ETDRS letters
• No history of Macular Edema
• Central Retinal Thickness of 250mics or more

Exclusion criteria

• Previous treatment.
• Other ophthalmic diseases. history of Nephropathy, heart diseases and pregnancy
• Media opacities

Trial design

0 participants in 2 patient groups

Group 1

Experimental group

Description:

Panretinal Photocoagulation + Bevacizumab

Treatment:

Drug: Bevacizumab

Group 2

Experimental group

Description:

Panretinal Photocoagulation

Treatment:

Procedure: Panretinal Photocoagulation