Avatar-Led Digital Therapeutic for Aiding Smoking Cessation in Sexual and Gender Minority Young Adults

Fred Hutchinson Cancer Center (FHCC)

Status: Completed

Conditions: Cigarette Smoking-Related Carcinoma

Treatments: Behavioral: Online Smoking Cessation Intervention; Other: Health Promotion and Education; Other: Questionnaire Administration

Study type: Interventional

Funder types: Other

Identifiers

NCT05847673

RG1123270 (Other Identifier)

NCI-2023-03050 (Registry Identifier)

Details and patient eligibility

About

This trial assesses the acceptability and preliminary efficacy of Empowered, Queer, Quitting, and Living (EQQUAL) smoking-cessation intervention for sexual and gender minority young adult smokers. The prevalence of tobacco use among sexual and gender minority (SGM) young adults is more than twice as high as non-SGM young adults, suggesting that existing SGM-related disparities in tobacco use will persist well into the foreseeable future unless sustained efforts are undertaken to address them. EQQUAL is an online smoking cessation intervention designed specifically for SGM young adult smokers, and may help them quit smoking.

Full description

OUTLINE: Participants are randomized to 1 of 2 arms.

ARM I: Participants receive self-guided, online quit smoking program, called EQQUAL Program A.

ARM II: Participants receive self-guided online quit smoking program, EQQUAL Program B.

Enrollment: 125 patients

Sex: All

Ages: 18 to 30 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• DEMOGRAPHIC CRITERIA:
• Participants must self-identify being between 18 and 30 years of age
• Participants must self-identify as a sexual and/or gender minority (i.e., a sexual orientation other than straight and/or gender that doesn't match sex assigned at birth)
• Participants must currently reside in the United States, with a United States (US) mailing address, and anticipate remaining in the US for the duration of the study (3 months)
• SMOKING CRITERIA:
• Participants must self-report smoking at least 1 cigarette per day in the 30 days prior to screening
• TREATMENT ACCESSIBILITY:
• Participants must self-report having at least weekly Internet access for the next three months
• Participants must self-report being willing and able to stream audio and video online for this study
• Participants must self-report current use of a personal email account
• Participants must self-report current use of text messaging
• OTHER CRITERIA:
• Participants must self-report that they are interested in participating in the study for themselves (versus [vs] someone else)
• Participants must self-report that they have not participated in one of our prior smoking cessation studies
• Participants must self-report that they are comfortable reading, writing, and speaking English
• Participants must self-report that they understand and agree to the conditions of compensation
• Participants must self-report that they are not currently incarcerated
• Participants must be willing to use the assigned intervention program, complete the study assessments, and consent to participate in this study
• Participants must be willing to upload a photo of themselves (face visible)

Exclusion criteria

• Participants must not be currently using other tobacco cessation treatments at the time of screening, including pharmacotherapy or behavioral support (but initiating these treatments during the study is allowed)
• Participants must not be a member of the same household as another research participant
• Having a Google voice number as their sole phone number

Trial design

Primary purpose: Prevention

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Single Blind

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125 participants in 2 patient groups

Arm I (EQQUAL A)

Experimental group

Description:

Participants receive self-guided online EQQUAL A program on study. Participants also receive motivational messages and smoking cessation information via text messages.

Treatment:

Other: Questionnaire Administration

Behavioral: Online Smoking Cessation Intervention

Other: Health Promotion and Education

Behavioral: Online Smoking Cessation Intervention

Arm II (EQQUAL B)

Active Comparator group

Description:

Participants receive self-guided online EQQUAL B program on study. Participants also receive motivational messages and smoking cessation information via text messages.

Treatment:

Other: Questionnaire Administration

Behavioral: Online Smoking Cessation Intervention

Other: Health Promotion and Education

Behavioral: Online Smoking Cessation Intervention