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Awake Prone Positioning for COVID-19 Acute Hypoxaemic Respiratory Failure

M

Mohammed VI University Hospital

Status

Completed

Conditions

Survival, Prosthesis
Oxygen Deficiency

Treatments

Other: Prone position

Study type

Observational

Funder types

Other

Identifiers

NCT05866289
unit critical care

Details and patient eligibility

About

The objective of our study is to evaluate the effectiveness of prone position in preventing intubation or death in spontaneously ventilated patients with COVID-19 with acute respiratory failure.

Full description

The COVID-19 pandemic has challenged the management of hypoxemic respiratory failure as limited ICU capacity is strained by a new high-mortality disease and large numbers of patients requiring prolonged periods of hospitalization, as well as respiratory support equipment such as ventilators and intensive care unit (ICU) beds.

If early and prolonged prone positioning (DV) reduces mortality in invasively ventilated patients with acute respiratory distress syndrome (ARDS), its role in conscious patients (DV vigil) remains a subject of debate and research.

This is a retrospective, monocentric, descriptive and analytical cohort conducted over a period of 22 months from March 2020 to December 2021 and involving 1069 patients hospitalized in the intensive care unit of the CHU Mohammed VI of Oujda for the management of acute respiratory failure caused by COVID-19.

Enrollment

1,069 patients

Sex

All

Ages

18 to 80 years old

Volunteers

Accepts Healthy Volunteers

Inclusion criteria

  • all patients (1069 patients) with ARDS due to SARS-cov2, confirmed by nasopharyngeal swab, who were hospitalized in the COVID-19 ICU from March 1, 2020 to December 31, 2021

Exclusion criteria

  • Patients with negative CRP
  • Younger than 18 years of age
  • Patients who died or intubated on the day of admission
  • Patients presented a contraindication

Trial design

1,069 participants in 2 patient groups

Includes 681 patients who were placed in prone position
Treatment:
Other: Prone position
Includes 388 patients who were placed in supine position

Trial documents
1

Trial contacts and locations

1

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Data sourced from clinicaltrials.gov

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