Ayurvedic Herbs in Diarrhea Predominant Irritable Bowel Syndrome (AHIB)

Universität Duisburg-Essen

Status: Completed

Conditions: Irritable Bowel Syndrome

Treatments: Drug: Placebo tea; Drug: Ayurvedic Herbs

Study type: Interventional

Funder types: Other

Identifiers

NCT01418066

11-4673 AHIB

Details and patient eligibility

About

In the present study the investigators are trying to evaluate the effect of Murraya koenigii leaves, Punica granatum and Curcuma which is administered to the patients in a combined form as tea. This study will help to evaluate the effect of these preparations scientifically in improving the IBS symptoms.

Full description

see above

Enrollment: 32 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Irritable Bowel Syndrome according to Rom-III
• Subtype Diarrhea or Alternating
• discomfort or pain > 1 times a week
• discomfort or pain > 4 on a Visual Analog Scale

Exclusion criteria

• Inflammatory bowel diseases (test results necessary)
• Lactose, Fructose Malabsorption (test results necessary)
• Celiac Disease
• Pregnancy or Breastfeeding
• Colectomy or Hemicolectomy >50cm
• Severe metabolic disorders, hormonal disorders, cardiac or respiratory failure, liver or renal diseases
• severe depression, psychotic or psychiatric disorders, substance abuse
• cancer within the last 5 years
• allergy to caraway
• acute inflammatory diseases

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Crossover Assignment

Masking: Quadruple Blind

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32 participants in 2 patient groups, including a placebo group

Placebo

Placebo Comparator group

Description:

Tea decoction made of Graminis Flores abd Maidis stigmata.

Treatment:

Drug: Placebo tea

Ayurvedic herbs

Experimental group

Description:

Tea decoction made of Murraya koenigii leaves, Punica granatum and Curcuma

Treatment:

Drug: Ayurvedic Herbs