Azathioprine in Recurrent Implantation Failure

Ain Shams University

Status and phase: Completed; Phase 2

Conditions: In Vitro Fertilization; Intracytoplsmic Sperm Injection; Recurrent Implantation Failure

Treatments: Drug: Placebo Oral Tablet; Drug: Azathioprine Pill

Study type: Interventional

Funder types: Other

Identifiers

NCT03498703

FW000372

Details and patient eligibility

About

Azathioprine increase pregnancy rate in patients with recurrent implantation failure

Enrollment: 64 patients

Sex: Female

Ages: 20 to 39 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• age: 20-39
• previous 3 or more failed ivf

Exclusion criteria

• intrauterine anomalies
• chronic systemic illness
• chronic pelvic conditions
• sensitivety to azathioprine

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Double Blind

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64 participants in 2 patient groups, including a placebo group

Azathioprine

Experimental group

Treatment:

Drug: Azathioprine Pill

Control

Placebo Comparator group

Treatment:

Drug: Placebo Oral Tablet