B-Thalasaemia Trait and Its Possible Cardioprotective Role

404 General Military Hospital, Larissa

Status: Unknown

Conditions: Coronary Artery Disease; Beta-Thalassemia Trait

Study type: Observational

Funder types: Other

Identifiers

NCT02428023

404 General Military Hospital

Details and patient eligibility

About

Our purpose is to investigate whether thallasaemia trait offers protection against cardiovascular events and whether this can be applied to specific characteristics of these people ( better lipid profile , better blood pressure profile) as scientific literature suggests.

Full description

Thallasaemia is a major problem , especially in countries around the Mediterranean sea.On the other hand ,thallasaemia trait has been shown ,in a small number of studies , to have a possible protective role against CAD and stroke.These kind of studies have been contacted in Greece also ,and usually they enroll a small number of participants. In the study, investigators will enroll 2500 subjects who serve in military units in Thesally Greece. Firstly investigators will estimate the prevalence of thallasaemia trait in this population , as it is very high in this region and at the same time investigators will retrospectively record data from their personal files (which are annually recorded).

Enrollment: 2,500 estimated patients

Sex: All

Ages: 18 to 57 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

1. voluntary participation,
2. Subjects with Thalassemia treat will be confirmed of their treat by electrophoresis -

Exclusion criteria

Trial design

2,500 participants in 2 patient groups

GrThalasaemia

Description:

estimation of IMT of the carotides arteries and calcium scoring

GrNormal

Description:

estimation of IMT of the carotides arteries and calcium scoring