Back to the Traditional: Anti-COX Drugs Can Improve the Outcome of COVID-19 Patients Admitted to ICU

Benha University

Status: Completed

Conditions: COVID-19 Disease

Treatments: Other: File inquiry

Study type: Observational

Funder types: Other

Identifiers

NCT04757792

RC1-2-2021

Details and patient eligibility

About

Retrospective multicenter study to evaluate the data of COVID-19 patients who were admitted to university hospitals in relation to their recent administration or maintenance on non-steroidal anti-inflammatory drugs (NSAID) prior to have COVID-19 disease and to analyze it in relation to outcome of these patients.

Full description

The data contained in hospital registry were collected, categorized into demographic, previous medical history, the use of NSAID as maintenance therapy or its recent administration before diagnosis of COVID-19 disease, presenting manifestations, laboratory and CT findings, applied therapies or interventions. Outcomes will be categorized as survival and non-survival outcome. Survivors will be subdivided as complete recovery or recovery with getting new morbidities. Mortality was subdivided as total hospital and ICU mortality. Data will be statistically analyzed in relation to outcomes

Enrollment: 475 patients

Sex: All

Volunteers: No Healthy Volunteers

Inclusion criteria

• assured diagnosis of COVID-19 by RT-PCR

Exclusion criteria

• No

Trial design

475 participants in 4 patient groups

No NSAID

Description:

included patients who did not receive NSAID prior to having COVID-19 disease

Treatment:

Other: File inquiry

Apsirin

Description:

included patients who received acetylsalicylic acid (ASA) prior to having COVID-19 disease

Treatment:

Other: File inquiry

Celecoxib

Description:

included patients who received celecoxib (CEL) prior to having COVID-19 disease

Treatment:

Other: File inquiry

Miscellaneous

Description:

included patients who received miscellaneous NSAID other than ASA or CEL prior to having COVID-19 disease

Treatment:

Other: File inquiry